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Lupron is STILL Not a Suicide Prophylaxis
13 reality based facts about puberty blockers to help Canadian lawmakers + judges
HPG Axis — Hypothalamic-Pituitary-Gonadal Axis (sex and reproduction)
HPA Axis — Hypothalamic-Pituitary-Adrenal Axis (stress response)
GnRH — Gonadotropin-Releasing Hormone (signals Pituitary)
GnRHa — Gondatropin-Releasing Hormone Analogue (a synthetic version of GnRH)
PuBl — Puberty Blockers, the woke euphemism for GnRHa (GnRHa is 4 times more potent than endogenous GnRH)
PPE — Personal Protective Equipment (double gloving for administering Lupron)
13 facts about puberty blockers progressives are hiding from you
The following 13 facts have solid valid + reliable evidence to support them. I have a ongoing reference list in Zotero and I add citations daily as I research and conduct literature searches. Whenever possible I try to include the relevant studies here in my Substack articles. References are now tacked onto the end.
Consider becoming a paid subscriber to help this publication research and write posts like this to expose the truth about Puberty Blockers aka Lupron and to debunk Gender Affirming Care.
Puberty Blocker (PuBl) is on the Hazardous Drugs List
Leuprolide Acetate is listed on the NIOSH Hazardous Drugs List. In Canada, it is listed on the provincial Hazardous Drug or Anti-Neoplastic Drugs lists. Occupational exposure requires PPE commensurate with any other parenteral cancer chemotherapy drug. The video which BC Children’s Hospital provides to instruct parents on administering Lupron to their kids does not include a warning about Universal Precautions required. The BCCH website which promotes Lupron for Pediatric Gender Dysphoria does not provide any Universal Precaution or Hazardous Drug warning. In fact the manufacturer’s video instructs the viewer to pull back the syringe and expel air — an obvious NO-NO with a Hazardous Drug. Are pregnant or conceiving mothers of Lupron Gender Dysphoria kids warned about the danger to them or their fetus? GnRHa is a teratogen.
PuBl has a 3 decades long history of significant + severe iatrogenic harm
Mounds of evidence, painstakingly collected for over 2 decades by former Emergency Room Nurse and Paralegal Lynne Millican. Lupron Victim Hub contains a wealth of damning information about Lupron’s debilitating effect on thousand and thousand of people, mainly women, who took it unsuspectingly when their doctor’s prescribed it unsuspectingly. TAP Pharmaceutical has a known history of exaggerating benefits and understating harmful effects of GnRHa, including falsifying clinical data supporting the use of Lupron for endometrial pain.
PuBl was intended to be a compassionate option to surgical castration
of the testicles in men with end stage metastatic prostate cancer — truly this made the synthesis of GnRH analogue so revolutionary! No more surgical removal of testicles to induce hypoandrogenism! Can you imagine the significance? How twisted that now we live in a time where GnRHa means the child patient will most certainly undergo surgical excision of the gonads? A drug created to save the gonads is being used to destroy them. Deliberately. As part of an experiment. To affirm an adolescent feeling.
No valid + reliable evidence exists to prove that PuBl saves kids’ lives
However much valid + reliable evidence exists to suggest that PuBl pose an iatrogenic danger to children. Over a quarter century of caseload evidence exist to prove that GnRH agonist is a poison to the human body and must be restricted severely. The deluge of useless studies that Gender Affirmation-biased researchers and clinicians publish, and the “trans kid” agenda which the compliant media continues to promote without critically questioning it, has caused pediatric medicine and counseling therapy also, to falter + fail society.
PuBl does not affirm a child, it lobotomises the hypothalamus and pituitary
The Hypothalamus is the smart centre and the Pituitary is the master gland of the brain. These two parts of the brain regulate and manage many other functions in the brain and nervous system and body. GnRH analogue lobotomises, ie neurally isolates + stuns + shrinks, these brain centres. To use a physical example: when you stunt the power centre and electric circuitry of your computer and interrupt its major OS upgrade, you could brick your computer, or otherwise render it unusable.
PuBl shuts down a major neuromodulation mechanism — the HPG Axis
PuBl are used to suppress sex drive in pedophiles because GnRH analogue is the chemical version of castration, de-sexing. The Hypothalamic-Pituitary-Gonadal Axis is the neuro-endocrine mechanism through which the gonads and the brain communicate. GnRH analogue severs the connection between the H+P and the G of the HPG. Sex isn’t just for procreation, it is for a bunch of other important metabolic and immune and thinking functions. When you chemically alter a child’s brain in this way before it has had a chance to fully grow, what are you doing? Probably not affirming them. Dis-homeostasis of the HPG Axis is a driver of neurodegeneration.
PuBl interrupts the neuromodulating effect of the Gonads on the adrenal system
PuBl interrupts the capacity of the sex organs to down-regulate immune and stress (flight or fight) responses. Estrogen enhances and Testosterone inhibits HPA function. Crudely meaning E intensifies and T stunts emotional reactivity. PuBl create an unnatural hormonal balance in the body by suppressing all gonadotropins. A 2014 case presentation of 3 young children with precocious puberty treated with PuBl (access a copy at the end of this list) concluded that, any factor that inhibits the action of estrogen or decreases its serum levels (such as seen with GnRHa) can potentially trigger mood instability or even psychotic symptoms because estrogen regulates dopamine DR-2 and 5H2Ta, and these two neurochemicals play a role in signalling the HPA Axis to respond to stress in a fight/flight/freeze as well as immune response.
PuBl impairs glucose metabolism and promotes insulin resistance
Estrogen receptors in the brain regulate body weight, energy expenditure and fat distribution. Multiple studies demonstrate an association between dysfunction of the reproductive neuroendocrine axis and insulin resistance, ie hyperinsulinema. Insulin plays a role in reproduction at the hypothalamic level. In fact, insulin research has begun to implicate insulin in the regulation of hypothalamic GnRH pulsatile activity.
Individuals with a damaged HPA Axis mimic a dysphoria symptom profile
Attachment disorders, childhood maltreatment, and Adverse Childhood Events (ACEs) damage the HPA Axis and produce altered and chronic stress responses. Children with neurodevelopmental disorders such as autism will have an atypical HPA Axis. These kids will present to clinicians + counsellors with the same symptom profile as sex/body/gender dysphoria. Differential diagnosis is key to screening theses kids out of the Gender Affirming Care pathway.
PuBl is not licensed to “affirm gender” in children
GnRHa makers have a consistent and lengthy history of exaggerating benefits and understating adverse reactions throughout the lifetime of their product. They continue to fudge the data, to manipulate comparatives to distort results. In fact TAP Holdings confessed to falsification of clinical data — Andrew Friedman made up the data to support treatment of endometrial disease. AbbVie knows well no evidence exists to support the use of GnRHa to affirm pediatric gender, it chooses to say nothing and in fact pays organisations and clinicians who promote Lupron as a remedy for gender confusion in kids.
97.5% of kids who socially transition by taking opposite sex names and pronouns end up on both puberty blockers + cross hormones.1
The transgender-friendly study by Olson, Gender Identity 5 Years After Social Transition, refers to a follow-up study that followed paediatric patients who had transitioned 1.5 years prior to the study for 3.8 years intended to tract the rates of transition in youth—published in Pediatrics August 2022. Olson inadvertently demonstrated that social transitioning locks a child into a path they cannot get themselves out of. Chemical castration + cross sex hormone results in the sterilization of the child. Olson raised questions about desistance, given the very high drop-off rate in the study — N = 317 at the start and N = 97 at the end. The extremely high levels of testosterone increase the likelihood of early hysterectomy d/t the toxic effect of testosterone on the female reproductive tract.
Puberty blockers are a euphemism for a chemical castration drug called GnRHa, marketed under the name Lupron in America.
Lupron is used by some American states to chemically castrate sex offenders + pedophiles to reduce recidivism. Chemical castration has a reasonably lengthy history in American jurisprudence and it remains highly controversial as a means of controlling offenders because its efficacy wanes when the offender stops taking the drug and ongoing use increases the risk of serious life threatening diseases such as metabolic syndrome, insulin resistance, and increased risk of cognitive decline and dementia.
The ACLU is fighting against the mandatory chemical castration of pedophiles/sex offenders and fighting for the mandatory chemical castration of gender non conforming children.
The Rolling Stone Magazine reported on the Alabama mandate to chemically castrate child sex offenders. The article points to the myriad of health concerns related to chemical castration and discusses the ethical implications and concerns of such an invasive procedure mandated by government. Rolling Stone Magazine also explored the efficacy of chemical castration for reducing recidivism.
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This figure comes from para 1 of the Discussion